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MESO PDRN-tFNA DERMA BOOST & RESTORE (5 x 5ml)

MESO PDRN-tFNA DERMA BOOST & RESTORE (5 x 5ml)

Contents:
  • 5 × vials of 5 ml

  • 5 × transparent pipettes

  • For five treatments

See the tabs for a detailed description of:
  • Ingredients

  • Treatment areas

  • Results

  • Treatment protocol

 

Unit price regardless of cocktail type

 


 

Pre-order now and get an additional 25% introductory discount.
The offer is valid only until March 1st.

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Stock status: NEW PRODUCT – Order NOW for delivery in March 2026
Model/Product no.: MST306

Option
  • I also want a MESOpower Pen kit with needle modules with a 10% discount

    I also want a MESOpower Pen kit with needle modules with a 10% discount

     

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Products and information are, pursuant to the Ministry of Health Guidelines of 28/03/2013

intended exclusively for professionals.

Customer service and support

Call us at
(+45) 71741108

Certified products

Produced in the EU

MESO PDRN‑tFNA DERMA BOOST & RESTORE

VEGAN Inflammation control, revitalization and advanced anti‑aging COCKTAIL

The cocktail is developed for non‑invasive professional skin renewal with PDRN,
the most researched ingredient for regeneration and anti‑inflammation.

Coming in Q1 2026

See the buttons above for detailed information about: Ingredients, Treatment areas and results, Instructions for use, Downloads

The treatment helps with

  • Tired and devitalized skin
  • Lack of moisture and dehydration
  • Loss of elasticity
  • Inflammation and redness
  • Early signs of aging
  • Uneven skin tone and pores

Treatment areas

  • Face
  • Neck
  • Décolleté
  • Hands
  • Eye area
  • Scars & irregularities
  • Post‑aesthetic treatments

Active ingredients

  • PDRN – regeneration & anti‑inflammation
  • Hyaluronic acid – hydration
  • Peptides – collagen support
  • Vitamins & amino acids – antioxidant & skin renewal
  • Minerals & essential lipids – barrier & strength
  • Panthenol & glycerin – soothing moisture

MESO PDRN‑tFNA DERMA BOOST &RESTORE is an advanced mesotherapy combining PDRN (Polydeoxyribonucleotide) and tFNA (tetrahedral DNA nanostructures) to promote skin regeneration. Both ingredients work at a cellular level to stimulate healing processes and improve skin texture.

What are PDRN and tFNA?

  • PDRN: A DNA‑based active, vegan-made, promoting tissue repair, reducing inflammation and increasing collagen production, which improves skin firmness and elasticity.

  • tFNA: Ultra‑short DNA fragments that enhance DNA repair, reduce inflammation and stimulate collagen production.

How does it work?

The treatment adds the active ingredients deep into the dermis and stimulates fibroblasts, which produce collagen. This results in firmer skin, reduced fine lines and a healthier, more youthful skin.

What do you achieve with MESO PDRN‑tFNA DERMA BOOST & RESTORE?

  • Improved skin structure: Increased firmness and elasticity.

  • Reduction of fine lines: Improved collagen production reduces wrinkles.

  • Improved hydration and glow: Skin gets better moisture balance and radiance.

  • Reduced inflammation: Suitable for sensitive skin and post‑aesthetic treatments.

How is it different from fillers?

While fillers add volume, MESO PDRN‑tFNA works on a deeper level to rebuild skin structure and health. It’s a long‑term solution, not just a temporary filler.

Usage in clinic:

  • Target group: Ideal for clients with aging signs or skin damage such as sun damage or scars.

  • Treatment schedule: 3–5 treatments with 3–4 weeks interval and maintenance every 3–6 months.

This treatment offers a non‑invasive solution for skin renewal and revitalization, perfect for professional practitioners who want to offer advanced, evidence‑based solutions.

Active ingredients

A breakthrough in modern mesotherapy
 

1. PDRN (Polydeoxyribonucleotide)

DNA fragments (vegan)

  • Supports skin regeneration
  • Improves moisture retention
  • Soothes inflammation

2. tFNA (Tetrahedral DNA Nanostructures)

Nano‑structured DNA fragments

  • Enhances cellular uptake
  • Stimulates DNA repair
  • Reduces oxidative stress

3. Hyaluronic acid
  • Provides hydration
  • Improves plumpness and skin density

4. Peptides
  • Copper peptides (skin repair)
  • Tripeptides / hexapeptides (firming, anti‑inflammatory)

5. Amino acids
  • Building blocks for collagen and elastin
  • Promotes smoother skin texture

6. Vitamins
  • Provide glow
  • Antioxidant protection

7. Antioxidants / soothing extracts
  • Glutathione
  • Centella Asiatica
  • Panthenol (Pro‑vitamin B5)

Applied technology

1. PDRN Regeneration Technology
  • Uses DNA fragments of controlled length
  • Supports cellular turnover and tissue‑like repair mechanisms

2. tFNA Nano‑Delivery System
  • DNA organized in a tetrahedral 3D nanostructure
  • Significantly improves penetration and stability
  • Increases bioavailability of active ingredients

3. Mesotherapy‑optimized molecular weight
  • Active substances designed for effective diffusion through micro‑channels (microneedling, etc.)
  • Low‑molecular hyaluronic acid and DNA fragments ensure better absorption

4. Antioxidant & anti‑inflammatory protection
  • Protects DNA from oxidative damage
  • Reduces redness and inflammation after treatment

5. Barrier‑repairing complex
  • Ceramides
  • Fatty acids
  • NMF components

Unique and Effective Ingredients: The Perfect Combination for Skin Regeneration and Anti‑Aging

  • AQUA: Water, used as solvent and base for the ingredients.
  • GLYCERIN: Moisturizer that attracts and retains moisture in the skin.
  • PANTHENOL: Moisturizes and soothes skin.
  • PHENOXYETHANOL: Preservative, prevents bacterial growth.
  • CALCIUM GLUCONATE: Supports skin regeneration and barrier function.
  • MAGNESIUM GLUCONATE: Soothes skin and helps moisture balance.
  • POTASSIUM GLUCONATE: Retains moisture in the skin.
  • XANTHAN GUM: Thickener, improves texture.
  • SODIUM LACTATE: Moisturizer, keeps skin hydrated.
  • SODIUM PCA: Moisturizes and improves skin elasticity.
  • PCA: Natural moisturizing factor.
  • ARGININE: Enhances collagen production and skin elasticity.
  • BUTYLENE GLYCOL: Moisturizes and increases absorption of ingredients.
  • SODIUM HYALURONATE: Attracts and holds water, gives deep hydration.
  • ASPARTIC ACID: Supports hydration and skin repair.
  • SORBITOL: Moisturizes skin and makes it soft.
  • ETHYLHEXYLGLYCERIN: Preservative with antimicrobial properties.
  • DISODIUM EDTA: Enhances preservative effectiveness.
  • LECITHIN: Nourishes and improves ingredient absorption.
  • TOCOPHERYL ACETATE: Vitamin E, protects against aging and environmental damage.
  • CITRIC ACID: Adjusts pH and promotes cell renewal.
  • PENTYLENE GLYCOL: Moisturizes and acts as solvent.
  • PHENYLALANINE: Supports collagen production and skin structure.
  • ISOLEUCINE: Helps skin repair and moisture retention.
  • PROLINE: Supports collagen synthesis and skin strength.
  • GLYCINE: Moisturizes and improves skin elasticity.
  • THREONINE: Strengthens skin’s moisture balance and barrier function.
  • ALANINE: Moisturizes and promotes cell renewal.
  • VALINE: Helps maintain skin’s moisture level.
  • HISTIDINE: Antioxidant, protects against environmental damage.
  • SERINE: Improves moisture barrier and skin health.
  • GLYCERYL LINOLEATE: Strengthens skin barrier and retains moisture.
  • GLYCERYL LINOLENATE: Preserves moisture and strengthens barrier.
  • RETINYL PALMITATE: Promotes skin renewal, reduces fine lines.
  • SODIUM ASCORBYL PHOSPHATE: Stable form of vitamin C, brightens skin and promotes collagen.
  • CAPRYLYL GLYCOL: Moisturizes and protects against bacterial growth.
  • 1,2‑HEXANEDIOL: Stabilizes and preserves the product.
  • POTASSIUM SORBATE: Prevents mold and yeast growth.

These ingredients work together to hydrate, protect and regenerate the skin, improving skin health and reducing signs of aging.

This is a groundbreaking formulation with ultra‑small molecules: Our mesotherapy formulations penetrate deep into the skin, ensuring better absorption and effectiveness, and distinguish themselves from others on the market by delivering faster and more targeted treatment for professional practitioners.


Conclusion

MESO PDRN‑tFNA DERMA BOOST & RESTORE is an advanced mesotherapy treatment combining a vegan-based PDRN (Polydeoxyribonucleotide) and tFNA (tetrahedral DNA nanostructures) to promote skin regeneration and revitalization.

This formulation works at a cellular level to strengthen the skin barrier, improve moisture balance and provide visible anti‑aging effects. The combination of PDRN and tFNA stimulates collagen production, reduces inflammation and promotes tissue renewal, resulting in firmer, more elastic and youthful skin.

The treatment is particularly effective for tired, dehydrated and stressed skin and works perfectly together with other cosmetic procedures such as microneedling and non‑invasive mesotherapy. The vegan‑based composition makes it ideal for clients seeking an ethical and hypoallergenic alternative to traditional, animal-derived treatments.

MESO PDRN‑tFNA DERMA BOOST & RESTORE thus offers an innovative solution for professional skin renewal, while meeting both ethical and skin‑sensitivity needs.

Ingredients 513
Treatment Areas and Results 514
How to use 515

ACTIVE INGREDIENTS – WITH DIRECT ANTI-AGE EFFECT

PDRN (Polydeoxyribonucleotides)
  • Stimulates cell renewal and DNA repair

  • Reduces inflammation and accelerates healing

  • Provides significantly improved skin texture, density, and radiance

tFNA (Triple-Helix Fragmented Nucleic Acids)
  • Enhances the skin’s regenerative response

  • Increases fibroblast activity → more collagen and elastin

  • Boosts renewal processes far deeper than classical mesotherapy products

Sodium Hyaluronate (Hyaluronic Acid)
  • Provides deep and long-lasting hydration

  • Minimises fine lines by filling moisture into the skin matrix

  • Improves elasticity and skin plumpness

Arginine
  • Stimulates collagen production

  • Improves elasticity and healing

Retinyl Palmitate (Vitamin A)
  • Promotes cell renewal and reduces fine lines

  • Brightens the skin and improves texture

Sodium Ascorbyl Phosphate (Vitamin C)
  • Antioxidant, reduces pigmentation

  • Stimulates collagen synthesis and evens out skin tone

Tocopheryl Acetate (Vitamin E)
  • Powerful antioxidant, protects against free radicals

  • Reduces aging caused by environmental damage


OTHER INGREDIENTS AND THEIR FUNCTIONS

AQUA
  • Base and solvent for all ingredients.
Glycerin
  • Binds and retains moisture → strengthens the skin barrier.
Panthenol (Provitamin B5)
  • Soothes, hydrates, and supports skin repair.
Phenoxyethanol
  • Preservative protecting against bacteria.
Calcium Gluconate
  • Strengthens barrier function and supports regeneration.
Magnesium Gluconate
  • Reduces irritation and supports moisture balance.
Potassium Gluconate
  • Moisture-binding and stabilises hydration.
Xanthan Gum
  • Provides texture and stability.
Sodium Lactate
  • Effective humectant → instant hydration.
Sodium PCA & PCA
  • Natural NMF components enhancing moisture and elasticity.
Butylene Glycol
  • Improves absorption of active ingredients.
AspARTIC Acid, Alanine, Glycine, Threonine, Valine, Histidine, Serine, Isoleucine, Proline, Phenylalanine

Amino acids that:

  • Support collagen formation

  • Repair skin tissue

  • Improve moisture balance and structure

Sorbitol
  • Hydrates and softens the skin.
Ethylhexylglycerin
  • Mild antimicrobial effect, improves preservation.
Disodium EDTA
  • Stabilises the formula and increases preservative efficiency.
Lecithin
  • Enhances penetration of active ingredients and nourishes the skin.
Citric Acid
  • Balances pH and stimulates mild exfoliation.
Pentylene Glycol
  • Hydrates and acts as a solvent.
Glyceryl Linoleate & Glyceryl Linolenate
  • Strengthen the lipid barrier → more elastic and resilient skin.
Caprylyl Glycol
  • Moisturising and antibacterial.
1,2-Hexanediol
  • Preserving and stabilising.
Potassium Sorbate
  • Prevents growth of mould and yeast.

OVERALL ANTI-AGE EFFECT IN THE TREATMENT

The ingredients work together to:

  • Promote cell renewal and deep regeneration

  • Reduce inflammation and redness

  • Strengthen barrier and elasticity

  • Minimise fine lines and improve texture

  • Increase hydration in all skin layers

  • Protect against free radicals and environmental damage

  • Improve radiance and skin tone

  • Shorten post-treatment recovery time

Treatment Areas

Face
– Skin rejuvenation, smoothing and improvement of overall skin texture.

Neck
– Reduces laxity and fine lines, providing firmer skin.

Décolletage
– Treats sun damage, pigmentation and texture irregularities.

Eye Area
– Reduces puffiness, fine lines, dark circles and tired appearance.

Hands
– Restores moisture and improves skin elasticity.

Scars and Irregularities
– Supports healing and smoothing of scars and post-inflammatory marks.

Post-aesthetic treatments
– Ideal after laser, microneedling, peeling and RF to speed up recovery.


Treatment Results

Improved skin texture and more even skin tone
– PDRN and tFNA stimulate cell renewal and create visibly smoother skin.

Increased hydration and elasticity
– Hyaluronic acid and amino acids bind moisture and improve skin firmness.

Reduced fine lines and wrinkles
– Activates collagen and elastin synthesis for more youthful skin.

Less redness and irritation
– Anti-inflammatory mechanisms soothe the skin and reduce sensitivity.

Increased radiance and vitality
– Vitamins C and E promote a healthy, even and more vibrant complexion.

Faster healing and shorter downtime
– PDRN accelerates the skin’s repair processes after treatment.

Strengthened skin barrier
– Lipids, amino acids and humectants improve the skin’s resilience.

Firming and improved skin quality
– tFNA and active peptides enhance skin density and elasticity.

Treatment Protocol – MESO PDRN-tFNA Derma Boost & Restore


1. Indications

The treatment is used for:

  • Devitalised, dry or ageing skin
  • Fine lines and loss of elasticity
  • Redness, inflammation and sensitivity
  • Uneven skin tone and post-inflammatory marks
  • Scars, texture irregularities and sun damage
  • Skin tightening and improved skin quality

2. Preparation Before Treatment

Clinic Preparation

  • Inform the client about the treatment process, results and expected downtime. Take a pre-treatment photo with makeup.
  • Disinfect all surfaces and equipment. Put on gloves. Cover the client’s hair with a headband/hairnet.
  • Open sterile meso modules: 24-non-traumatic and optionally 3- or 1-point modules for deep lines or scars.
  • Open the Mesococktail vial.

Client Preparation

  • Remove makeup with Meso Balancing Cleanser. Take a pre-treatment photo of the cleansed skin. 2 min
  • Cleanse the skin with Meso Pure Peel. 2 min
  • Treat the skin using circular movements with the 24-non-traumatic module. Use other needle modules as needed for lines, scars or laxity using the “press and lift” technique. 20 min
  • Apply Meso Anti-age mask. 20–25 min
  • Finish with Meso Lift and Protect cream. 2 min

3. Technique and Dosage

Recommended needle depth for microneedling / non-invasive mesotherapy

  • Face: 0.3–0.5 mm
  • Neck: 0.3–0.4 mm
  • Décolleté: 0.3–0.5 mm
  • Eye area: 0.2–0.3 mm
  • Hands: 0.3–0.5 mm
  • Scars/texture: 0.5–0.7 mm (depending on skin thickness)

Recommended product amount per treatment

  • 3–4 ml for the face
  • 1–2 ml for the neck
  • 1–2 ml for the décolleté
  • 0.5–1 ml per hand
  • 1–3 ml for specific scars/areas
  • Typical total usage: 4–5 ml per session

Technique

  • Work in systematic zones: décolleté → neck → jawline → mouth → cheeks → forehead
  • Apply a thin, even layer of product throughout the treatment.
  • Use smooth, overlapping strokes for optimal penetration.
  • For scars/texture: use “press and lift” for deeper stimulation.
  • Avoid over-treating (no bleeding with non-invasive techniques).

4. Treatment Course

Standard course

  • 4–6 treatments
  • Interval: 7–14 days

Intensive anti-age course

  • 6–8 treatments
  • Interval: 7 days

Maintenance

  • One treatment every 4–6 weeks
  • Alternatively: 2 treatments every 3 months

5. Aftercare (24–72 hours)

Immediately after the treatment

  • Apply soothing serum or cream (hypoallergenic).
  • Finish with SPF 50 (mineral or medical grade). Meso Lift and Protect.

The client must avoid for 24–48 hours

  • Makeup (24 hours)
  • Sauna, swimming, solarium
  • Intense exercise or heat
  • Direct sunlight
  • Active acids, retinol or AHA/BHA
  • Harsh skincare products and scrubs

Expected reactions

  • Mild redness 1–24 hours
  • Slight swelling around the eyes (rare)
  • Warmth and mild sensitivity

Recommended home care

  • Soothing and hydrating cream twice daily
  • Mild fragrance-free cleanser
  • Plenty of water
  • Daily SPF 50

6. Long-term Maintenance

For optimal and long-lasting results, it is recommended:

  • A boost treatment every 4–6 weeks
  • Annual or semi-annual intensive courses (4 treatments)
  • Combination with peels, LED therapy or mesolift for additional effect
  • Avoid smoking and excessive UV exposure
  • Use SPF daily

7. Combination With Other Treatments

Treatment

Can be combined?

Recommended interval

Laser (non-ablative)

Yes

MESO 7 days after laser

Microneedling

Yes

Same day (if MESO is used as serum)

Chemical peel (mild)

Yes

Before MESO or 7 days after

RF / Skin Tightening

Yes

7–10 days apart

Fillers/Botox

Yes

Botox: 3–5 days before/after
Fillers: 7–14 days before/after

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